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  • Recent Progress in Continuo...
    Yu, Tao; Jiao, Jiao; Song, Peidong; Nie, Wenzheng; Yi, Chunhai; Zhang, Qian; Li, Pengfei

    ChemSusChem, June 8, 2020, Letnik: 13, Številka: 11
    Journal Article

    To achieve a safe, efficient, and sustainable (even fully automated) production for the continuous‐flow hydrogenation reactions, which is among the most often used reactions in chemical synthesis, new catalyst types and immobilization methods as well as flow reactors and technologies have been developed over the last years; in addition, these approaches have been combined with new and transformational technologies in other fields such as artificial intelligence. Thus, attention from academic and industry practitioners has increasingly focused on improving the performance of hydrogenation in flow mode by reducing the reaction times, increasing selectivities, and achieve safe operation. This Minireview aims to summarize the most recent research results on this topic with focus on the advantages, current limitations, and future directions of flow chemistry. The art of hydrogenation in flow: Considering cost‐effective and environmentally sustainable manufacturing, continuous‐flow techniques have become an inevitable trend. Among these, continuous‐flow hydrogenation has received considerable attention as it provides a safe and efficient platform for the synthesis of organic compounds at low reaction temperatures and pressures. In this Minireview, recent progress made in continuous‐flow hydrogenations is summarized, pointing out the advantages and future perspectives of flow chemistry.