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Nesterov, Evgueni E.; Skoch, Jesse; Hyman, Bradley T.; Klunk, William E.; Bacskai, Brian J.; Swager, Timothy M.
Angewandte Chemie (International ed.), August 26, 2005, Letnik: 44, Številka: 34Journal Article
Routine diagnostics and studies of Alzheimer's disease might benefit form the noninvasive optical imaging of amyloid‐β plaques in the brain. A rational design strategy for in vivo amyloid‐imaging agents that enter the brain and selectively stain amyloid plaques is presented (see picture), and properties of a promising lead biomarker candidate are reported.
