•In this paper, we designed, simulated and analyzed high efficiency of SnS-based solar cells.•Photovoltaic performance of tilted nanocolumns SnS-based solar cells was studied.•The best efficiency was found for the sample prepared at highest deposition angle. In this paper, we designed, simulated and analyzed high efficiency of SnS-based solar cells. This work is related to the influence of a glancing angle deposition (GLAD) technique for deposition of SnS layer, on the photovoltaic performance of SnS-based solar cells. The photovoltaic parameters have been calculated for the samples prepared at different oblique incident flux angles (α = 0°, 45°, 55°, 65°, 75°, and 85°). The best efficiency was found for the sample prepared at α = 85°. We simulated the J-V characteristics and showed how the absorber layer that prepared by GLAD technique at different incident flux angles, influence the short-circuit current density (Jsc), open-circuit voltage (Voc), fill factor (FF), and efficiency (η) of solar cell.