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Kinoshita, Keisuke; Yamaguchi, Miyuki; Sasou, Hirohisa; Konishi, Hideyuki; Manabe, Kei
Chemical & pharmaceutical bulletin, 02/2023, Letnik: 71, Številka: 2Journal Article
Palladium-catalyzed, hydroxy-group-directed C–H arylation of 1,1′-biphenyl-2-ols with chloroarenes was performed. The reaction showed a broad substrate scope and was successfully applied to pharmaceuticals containing a chloro group. Using 2-heteroarylphenols instead of 1,1′-biphenyl-2-ols also yielded the desired products. The arylated product was further transformed into a triphenylene derivative.
