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  • Integrated Bioprocess Devel...
    Cornelissen, G.; Leptien, H.; Pump, D.; Scheffler, U.; Sowa, E.; Radeke, H.H.; Luttmann, R.

    IFAC Proceedings Volumes, June 2001, 2001-06-00, Letnik: 34, Številka: 5
    Journal Article

    An integrated bioprocess is built up for production of an antagonist of recombinant monocyte chemoattractant protein-1 with Pichia pastoris. The process line based on full automated cultivation procedures includes micro-and ultra-filtration membrane modules for in-situ interactions as well as liquid chromatography methods for post cultivation opcrations.