The purpose of this qualitative case study is two-fold: (a) describe the implementation of a stop-motion animation video activity to support students' understanding of cell processes, and (b) present research findings about students' beliefs and use of iPads to support their creation of stop-motion videos in an introductory biology course. Data indicated that students used the devices extensively to access, seek, and share information related to cell processes, which led to their increased familiarity with using the iPad to support their learning. Using iPads and apps enriched students learning experiences by providing them with a creative way to demonstrate their understanding of content, enhanced their communication skills, and provided them with an alternative means for gathering and sharing supplementary resources.