To help them through this arduous treatment, physicians and nurses trained community health workers, provided nutritional, economic, and psychosocial support, and invested in medications to ease these side-effects.2 These approaches resulted in outcomes that were far better than predicted, and helped change the dogma that, among people of low socioeconomic status, multidrug-resistant tuberculosis need be a death sentence.3 Some of those cured, even after enduring severe toxicities, became praiseworthy advocates for those facing the same grim prospects. When considered in context with other data from prospective clinical trials, these results argue strongly for the inclusion of bedaquiline and linezolid in treatment for almost any patient with multidrug-resistant tuberculosis, along with better tolerated later-generation fluoroquinolones such as levofloxacin or moxifloxacin. ...although this study can compare the relative effectiveness of specific drug combinations, it remains difficult to infer what might be the safest and most effective ones, and the ideal duration of therapy for incident and chronic cases of extensively drug-resistant tuberculosis.