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Knust, Barbara; Brown, Shelley; de St. Maurice, Annabelle; Whitmer, Shannon; Koske, Sarah E; Ervin, Elizabeth; Patel, Ketan; Graziano, James; Morales-Betoulle, Maria E; House, Jennifer; Cannon, Deborah; Kerins, Janna; Holzbauer, Stacy; Austin, Connie; Gibbons-Burgener, Suzanne; Colton, Leah; Dunn, John; Zufan, Sara; Choi, Mary Joung; Davis, William R; Chiang, Cheng-Feng; Manning, Craig R; Roesch, Linda; Shoemaker, Trevor; Purpura, Lawrence; McQuiston, Jennifer; Peterson, Dallin; Radcliffe, Rachel; Garvey, Ann; Christel, Ellen; Morgan, Laura; Scheftel, Joni; Kazmierczak, James; Klena, John D; Nichol, Stuart T; Rollin, Pierre E
The Journal of infectious diseases, 10/2020, Letnik: 222, Številka: 8Journal Article
Abstract Background During 2017, a multistate outbreak investigation occurred after the confirmation of Seoul virus (SEOV) infections in people and pet rats. A total of 147 humans and 897 rats were tested. Methods In addition to immunoglobulin (Ig)G and IgM serology and traditional reverse-transcription polymerase chain reaction (RT-PCR), novel quantitative RT-PCR primers/probe were developed, and whole genome sequencing was performed. Results Seventeen people had SEOV IgM, indicating recent infection; 7 reported symptoms and 3 were hospitalized. All patients recovered. Thirty-one facilities in 11 US states had SEOV infection, and among those with ≥10 rats tested, rat IgG prevalence ranged 2%–70% and SEOV RT-PCR positivity ranged 0%–70%. Human laboratory-confirmed cases were significantly associated with rat IgG positivity and RT-PCR positivity (P = .03 and P = .006, respectively). Genomic sequencing identified >99.5% homology between SEOV sequences in this outbreak, and these were >99% identical to SEOV associated with previous pet rat infections in England, the Netherlands, and France. Frequent trade of rats between home-based ratteries contributed to transmission of SEOV between facilities. Conclusions Pet rat owners, breeders, and the healthcare and public health community should be aware and take steps to prevent SEOV transmission in pet rats and to humans. Biosecurity measures and diagnostic testing can prevent further infections. An investigation of Seoul virus infections in pet rats and people in the US found 31 infected facilities and 17 people with recent infections—all recovered with 3 hospitalized. Frequent trade of rats contributed to transmission of SEOV between facilities.
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Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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