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Purushe, Janaki; Fouts, Derrick E.; Morrison, Mark; White, Bryan A.; Mackie, Roderick I.; Coutinho, Pedro M.; Henrissat, Bernard; Nelson, Karen E.
Microbial ecology, 11/2010, Letnik: 60, Številka: 4Journal Article
The Prevotellas comprise a diverse group of bacteria that has received surprisingly limited attention at the whole genome-sequencing level. In this communication, we present the comparative analysis of the genomes of Prevotella ruminicola 23 (GenBank: CP002006) and Prevotella bryantii B₁4 (GenBank: ADWO00000000), two gastrointestinal isolates. Both P. ruminicola and P. bryantii have acquired an extensive repertoire of glycoside hydrolases that are targeted towards non-cellulosic polysaccharides, especially GH43 bifunctional enzymes. Our analysis demonstrates the diversity of this genus. The results from these analyses highlight their role in the gastrointestinal tract, and provide a template for additional work on genetic characterization of these species.
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