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  • Second-generation Hybrid ca...
    Poljak, Mario; Marin, Irena J; Seme, Katja; Brinovec, Vladimir; Matičič, Mojca; Meglič-Volkar, Jelka; Lešničar, Gorazd; Vince, Adriana

    Journal of virological methods, 09/2001, Letnik: 97, Številka: 1
    Journal Article

    The performance of the Digene Hybrid Capture II HBV DNA Test HC II and the Roche Cobas Amplicor Monitor Test (Cobas-HBV) was evaluated on 252 serum samples. One hundred and seventy-three samples were HBV DNA positive and 75 HBV DNA negative by both assays. Four samples were HBV DNA positive by Cobas-HBV only. Linear regression analysis showed that the HBV DNA concentrations obtained from both assays were significantly related ( n=173, r=0.976, P<0.0001). The results of the study show that Hybrid capture II and Cobas-HBV could be used equally in the management for patients with chronic HBV infection.