Prior to the year 2000, non‐aqueous uranium chemistry mainly involved metallocene and classical alkyl, amide, or alkoxide compounds as well as established carbene, imido, and oxo derivatives. Since then, there has been a resurgence of the area, and dramatic developments of supporting ligands and multiply bonded ligand types, small‐molecule activation, and magnetism have been reported. This Review 1) introduces the reader to some of the specialist theories of the area, 2) covers all‐important starting materials, 3) surveys contemporary ligand classes installed at uranium, including alkyl, aryl, arene, carbene, amide, imide, nitride, alkoxide, aryloxide, and oxo compounds, 4) describes advances in the area of single‐molecule magnetism, and 5) summarizes the coordination and activation of small molecules, including carbon monoxide, carbon dioxide, nitric oxide, dinitrogen, white phosphorus, and alkanes. Rise like a phoenix? In the last several years, there has been a resurgence of non‐aqueous uranium chemistry, in particular dealing with the development of new ligand classes and complexes with multiple bonding, single‐molecule magnetism, and the activation of small molecules, such as N2, CO2, and alkanes. Owing to its unusual coordination properties, uranium is remarkably different from transition metals, but also from other actinides.