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Boekhoven, Job; Rubert Pérez, Charles M.; Sur, Shantanu; Worthy, Amanda; Stupp, Samuel I.
Angewandte Chemie (International ed.), November 11, 2013, Letnik: 52, Številka: 46Journal Article
A molecular host, β‐cyclodextrin (CD), covalently attached to an alginate matrix enables dynamic control of cue display through exchange of guest molecules. Addition of soluble RGDS‐containing guest molecules to culture medium induced focal adhesion formation and spreading of 3T3 fibroblasts on the otherwise non‐spreading alginate surface. The spreading could be reversed by adding competitive guest molecules bearing the mutated non‐bioactive sequence RGES.
