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Boyer, Frederick E.; Vara Prasad, J.V.N.; Choy, Allison L.; Chupak, Louis; Dermyer, Michael R.; Ding, Qizhu; Huband, Michael D.; Jiao, Wenhua; Kaneko, Takushi; Khlebnikov, Vladimir; Kim, Ji-Young; Lall, Manjinder S.; Maiti, Samarendra N.; Romero, Karina; Wu, Xiujuan
Bioorganic & medicinal chemistry letters, 08/2007, Letnik: 17, Številka: 16Journal Article
A novel series of conformationally-restricted oxazolidinones were synthesized which possess a fused pyrazole ring substituted with various alkyl, aryl and heteroaryl substituents A novel series of conformationally-restricted oxazolidinones was synthesized which possess a fused pyrazole ring substituted with various alkyl, aryl and heteroaryl substituents. A number of analogs exhibited potent activity against both Gram-positive and fastidious Gram-negative organisms.
