The impact of biogenic emissions on ozone and PM2.5 levels over Europe is assessed using CMAQ. Biogenic emissions are predicted to increase Max8hrO3 mixing ratios by 5.7% and to decrease PM2.5 concentrations by 1.9%, increasing PM2.5_OC by 13.6% and decreasing PM2.5_SO4, PM2.5_NO3 and PM2.5_NH4 by 5.6%, 3.7% and 5.6%, respectively, on average over Europe due to their interactions with anthropogenic emissions. A suite of perturbations in temperature is imposed individually on the base case conditions in order to determine the sensitivities to air temperature changes. Temperature increases of 1, 2 or 3° K suggest an average increase in Max8hrO3 mixing ratios of 0.9%, 1.8% or 2.9%, respectively, and an average decrease in daily average PM2.5 concentrations of 2.5%, 4.2% and 5.8%, respectively, increasing PM2.5_OC and decreasing PM2.5_SO4, PM2.5_NO3 and PM2.5_NH4 component concentrations on average over Europe. In order to examine if abatement measures for anthropogenic emissions could offset ozone increases in higher temperatures and their effect on PM2.5 concentrations, a simulation with a domain wide reduction in anthropogenic NOx emissions of 10% is performed. This is estimated to reduce Max8hrO3 mixing ratios by 1.3% on average over Europe. However, NOx reduction is estimated to increase Max8hrO3 in VOCs limited areas. The reduction in anthropogenic NOx emissions is predicted to reduce PM2.5 concentrations by 1.0% enhancing the reduction simulated, here, with temperature increase but further modifying PM2.5 component concentrations. •Biogenic emissions are simulated to increase O3, locally, while reduce PM2.5 levels.•Sensitivity to temperature increase is positive for O3 and negative for PM2.5 levels.•NOx emissions reduction lowers O3, in general, but leads to some local increases.•NOx emissions reduction lowers PM2.5 and modifies PM2.5 composition.