E-viri
Recenzirano
-
Yu, Le; Abbas Abedi, Syed Ali; Lee, Jeongjin; Xu, Yunjie; Son, Subin; Chi, Weijie; Li, Mingle; Liu, Xiaogang; Park, Jae Hyung; Kim, Jong Seung
Angewandte Chemie International Edition, August 7, 2023, Letnik: 62, Številka: 32Journal Article
Photoacoustic imaging (PAI), a state‐of‐the‐art noninvasive in vivo imaging technique, has been widely used in clinical disease diagnosis. However, the design of high‐performance PAI agents with three key characteristics, i.e., near‐infrared (NIR) absorption (λabs>800 nm), intense PA signals, and excellent photostability, remains a challenging goal. Herein, we present a facile but effective approach for engineering PAI agents by amplifying intramolecular low‐frequency vibrations and enhancing the push‐pull effect. As a demonstration of this blended approach, we constructed a PAI agent (BDP1‐NEt2) based on the boron‐dipyrromethene (BODIPY) scaffold. Compared with indocyanine green (ICG, an FDA‐approved organic dye widely utilized in PAI studies; λabs=788 nm), BDP1‐NEt2 exhibited a UV/Vis‐NIR spectrum peaked at 825 nm, superior in vivo PA signal intensity and outstanding stability to offer improved tumor diagnostics. We believe this work provides a promising strategy to develop the next generation of PAI agents. In this work, we present a facile but effective approach for engineering photoacoustic imaging (PAI) agents by amplifying intramolecular low‐frequency vibrations and enhancing the push‐pull effect. As a demonstration of this blended approach, we constructed a PAI agent (BDP1‐NEt2) based on the boron‐dipyrromethene (BODIPY) scaffold, which met key requirements of high‐quality PAI.
Avtor
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.