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  • Have changing pneumococcal ...
    Lim, Gillian H; Wormsbecker, Anne E; McGeer, Allison; Pillai, Dylan R; Gubbay, Jonathan B; Rudnick, Wallis; Low, Don E; Green, Karen; Crowcroft, Natasha S; Deeks, Shelley L

    Vaccine, 05/2013, Letnik: 31, Številka: 24
    Journal Article

    Highlights • Impact of Ontario's pneumococcal conjugate vaccine (PCV) programme was investigated. • Invasive pneumococcal disease due to PCV7 serotypes declined in children <5 years. • There is also some suggestion of early impact among infants of the change to PCV10. • Evidence of herd immunity and serotype replacement was observed. • Our results also demonstrate the substantial burden of disease among older adults.