E-viri
Recenzirano
Odprti dostop
-
Bouza, Emilio; Tattevin, Pierre; Habib, Gilbert; Tan, Ren; Fortes, Claudio Querido; Siciliano, Rinaldo Focaccia; Cortes, Claudia; Kogan, Silvia; Spelman, Denis; Jones, Phillip; Harkness, John; Ryan, Suzanne; Jones, Phillip; Post, Jeffrey; Ryan, Suzanne; Gattringer, Rainer; Andrade, Adriana Ribas; Strabelli, Tania Mara Varejao; Oliveira Ramos, Auristela; Weksler, Clara; Fernandez, Ricardo; Bukovski, Suzana; Rudez, Igor; Alla, Francois; Casalta, Jean‐Paul; Fournier, Pierre‐Edouard; Raoult, Didier; Donnio, Pierre Yves; Michelet, Christian; Jeu, Antoine; Tribouilloy, Christophe; Leroy, Joel; Athanasia, Sophia; Deliolanis, Ioannis; Giamarellou, Helen; Thomas, Tsaganos; Paniara, Olga; Papanicolaou, Konstantinos; Paniara, Olga; Pyros, John; Francis, Johnson; Israel, Sarah; Strahilevitz, Jacob; Durante‐Mangoni, Emanuele; Senese, Alessandra; Cecchi, Enrico; De Rosa, Francesco; Forno, Davide; Imazio, Massimo; Toniolo, Antonio; Goglio, Antonio; Rizzi, Marco; Carosi, Giampiero; Signorini, Liana; Kanafani, Zeina; Kanj, Souha S.; Abidin, Imran; Tamin, Syahidah Syed; Meer, Jan T.M.; Chambers, Stephen; Morris, Arthur; Raymond, Nigel; Butkevich, O.M.; Chipigina, Natalia; Vadim, Kulichenko; Liew, Yee‐Yun; Tan, Ru‐San; Logar, Mateja; Hansa, Cass; Almela, Manuel; Armero, Yolanda; Azqueta, Manuel; Cervera, Carlos; Gatell, Jose M.; Paré, Carlos; Rovira, Irene; Garcia Fernández, Miguel Angel; Roda, Jorge; Solis, Jorge; Olaison, Lars; Pussadhamma, Burabha; Watkin, Richard; Klein, John L.; Mudrick, Daniel; Stryjewski, Martin; Woods, Christopher W.; Lerakis, Stamatios; Cantey, Robert; Bonilla, Hector; Salstrom, Sara‐Jane; Corey, G. Ralph; Dixon, Christy C.; Fowler, Vance G.; Jones‐Richmond, Marian; Stafford, Judy; Stafford, Judy; Cabell, Christopher H.; Fowler, Vance G.; Bayer, Arnold S.; Fowler, Vance G.
Journal of the American Heart Association, 04/2016, Letnik: 5, Številka: 4Journal Article
Background Host factors and complications have been associated with higher mortality in infective endocarditis (IE). We sought to develop and validate a model of clinical characteristics to predict 6‐month mortality in IE. Methods and Results Using a large multinational prospective registry of definite IE (International Collaboration on Endocarditis ICE–Prospective Cohort Study PCS, 2000–2006, n=4049), a model to predict 6‐month survival was developed by Cox proportional hazards modeling with inverse probability weighting for surgery treatment and was internally validated by the bootstrapping method. This model was externally validated in an independent prospective registry (ICE‐PLUS, 2008–2012, n=1197). The 6‐month mortality was 971 of 4049 (24.0%) in the ICE‐PCS cohort and 342 of 1197 (28.6%) in the ICE‐PLUS cohort. Surgery during the index hospitalization was performed in 48.1% and 54.0% of the cohorts, respectively. In the derivation model, variables related to host factors (age, dialysis), IE characteristics (prosthetic or nosocomial IE, causative organism, left‐sided valve vegetation), and IE complications (severe heart failure, stroke, paravalvular complication, and persistent bacteremia) were independently associated with 6‐month mortality, and surgery was associated with a lower risk of mortality (Harrell's C statistic 0.715). In the validation model, these variables had similar hazard ratios (Harrell's C statistic 0.682), with a similar, independent benefit of surgery (hazard ratio 0.74, 95% CI 0.62–0.89). A simplified risk model was developed by weight adjustment of these variables. Conclusions Six‐month mortality after IE is ≈25% and is predicted by host factors, IE characteristics, and IE complications. Surgery during the index hospitalization is associated with lower mortality but is performed less frequently in the highest risk patients. A simplified risk model may be used to identify specific risk subgroups in IE.
Avtor
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.