To compare the efficacy of 2-octylcyanoacrylate (Dermabond; Ethicon Inc) with standard suture repair in the management of cervical laminoplasty. Fourty-five patients were enrolled in this study. Twenty-two patients were using Dermabond, and 23 were repaired using standard suture. All patients underwent surgery in 2010 and were observed three months or more after operation. Operation time, prone position time, incision length, intraoperative blood loss, days of drain and gauze removal and times to replace the gauze were examined. There were no adverse events in both groups. Significant difference in operation and prone position time, intraoperative blood loss, days of drain removal were not observed. The average days required for gauze removal using Dermabond was 6.73 days, which was significantly less than that required for suture repair (11.87 days) (p<0.05). And the average number of times to replace the gauze using Dermabond was 3.86, which was significantly less than that required for suture repair (5.22 times) (p<0.05). In the management of cervical laminoplasty, Dermabond is an effective repair technique.