Libraries in Nigeria have long struggled to adequately serve the information needs of visually impaired individuals, particularly those who are literate. Despite this, scholarly research addressing these issues in South-Eastern Nigeria is lacking, highlighting the urgency of investigating predictors of user satisfaction among visually impaired students in SLMCs. The research design utilizes a survey methodology across four states in South-Eastern Nigeria, encompassing a total population of 95 individuals. Data collection involves administering questionnaires to visually impaired students and SLMC personnel, followed by comprehensive data analysis using descriptive and inferential statistical techniques. Findings reveal a positive correlation between information needs, library accessibility, and user satisfaction, while library services and media-format availability did not significantly influence user satisfaction. Impediments to user satisfaction include inadequacy of media formats, contents, outdated materials, lack of equipment, and recording studios. Addressing these challenges is crucial to improving library engagement and user satisfaction among visually impaired students in South-Eastern Nigeria, ultimately fostering more inclusive and supportive educational environments.