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Gauckler, Philipp; Shin, Jae Il; Alberici, Federico; Audard, Vincent; Bruchfeld, Annette; Busch, Martin; Cheung, Chee Kay; Crnogorac, Matija; Delbarba, Elisa; Eller, Kathrin; Faguer, Stanislas; Galesic, Kresimir; Griffin, Siân; Hrušková, Zdenka; Jeyabalan, Anushya; Karras, Alexandre; King, Catherine; Kohli, Harbir Singh; Maas, Rutger; Mayer, Gert; Moiseev, Sergey; Muto, Masahiro; Odler, Balazs; Pepper, Ruth J.; Quintana, Luis F.; Radhakrishnan, Jai; Ramachandran, Raja; Salama, Alan D.; Segelmark, Mårten; Tesař, Vladimír; Wetzels, Jack; Willcocks, Lisa; Windpessl, Martin; Zand, Ladan; Zonozi, Reza; Kronbichler, Andreas
Autoimmunity reviews, 11/2020, Letnik: 19, Številka: 11Journal Article
Primary forms of minimal change disease and focal segmental glomerulosclerosis are rare podocytopathies and clinically characterized by nephrotic syndrome. Glucocorticoids are the cornerstone of the initial immunosuppressive treatment in these two entities. Especially among adults with minimal change disease or focal segmental glomerulosclerosis, relapses, steroid dependence or resistance are common and necessitate re-initiation of steroids and other immunosuppressants. Effective steroid-sparing therapies and introduction of less toxic immunosuppressive agents are urgently needed to reduce undesirable side effects, in particular for patients whose disease course is complex. Rituximab, a B cell depleting monoclonal antibody, is increasingly used off-label in these circumstances, despite a low level of evidence for adult patients. Hence, critical questions concerning drug-safety, long-term efficacy and the optimal regimen for rituximab-treatment remain unanswered. Evidence in the form of large, multicenter studies and randomized controlled trials are urgently needed to overcome these limitations.
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Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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