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Sauroxine reduces memory retention in rats and impairs hippocampal long-term potentiation generationVallejo, Mariana; Carlini, Valeria; Gabach, Laura; Ortega, M.G; L. Cabrera, José; de Barioglio, Susana Rubiales; Pérez, Mariela; Agnese, Alicia M
Biomedicine & pharmacotherapy, 07/2017, Letnik: 91Journal Article
Highlights • Sauroxine is an alkaloid from Phlegmariurus saururus. • It inhibited the hippocampal long-term potentiation when was tested in vitro. • Sauroxine also impaired memory retention in Step-down test. • This alkaloid crossed the blood-brain barrier reaching the brain. • Sauroxine could be a potential therapeutic amnesic agent.
