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Hammoud, Leila; León, Francisco; Brouard, Ignacio; Gonzalez-Platas, Javier; Benayache, Samir; Mosset, Paul; Benayache, Fadila
Tetrahedron letters, 07/2018, Letnik: 59, Številka: 27Journal Article
Display omitted •Phytochemical study of Saharan medicinal plant.•Two new astericunolides and one humulene were isolated.•X-ray of astericunolide I. Three new sesquiterpene-humulenes, (−)- asteriscunolides I (1), J (2) and (−)-(2Z,6E,9Z)-8-oxo-1α-acetoxy-2,6,9-humulatrien-12-oic acid (3) were isolated from the leaves-flowers of the Saharan medicinal plant Asteriscus graveolens along with six known compounds. The structures of the compounds were determined on the basis of spectroscopic mono and bidimensional NMR, mass spectrometry and by single-crystal X-ray diffraction. Compounds 1–3 were evaluated for cytotoxic assay, no significant activity was detected.
