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  • Double Antiplatelet Therapy...
    Gilard, Martine, MD, PhD; Morice, Marie Claude, MD

    Journal of the American College of Cardiology, 05/2015, Letnik: 65, Številka: 20
    Journal Article

    Of 11,648 patients randomized in the DAPT trial, 3,576 (30.7%) presented with acute MI; 1,680 of the MI patients (47%) presented with initial ST-segment elevation MI and the remainder with non-ST-segment elevation MI. Because this variable was not factored in the randomization, the characteristics of the 2 groups differed: non-MI patients were older; more often female; and showed higher rates of diabetes, peripheral disease, and prior percutaneous coronary intervention. According to the investigators, this increase in noncardiovascular mortality was not exclusively caused by an increase in bleeding-related death.