Development of innovation, diffusion canbe used to increasethe productivity or competitiveness of the institution or nation. So, strengthening the innovation system becomes a very important thing to do in many countries, including Indonesia. In the era of globalization, where the development of science and technology is so dynamic, the development of innovation system in a country is no longer possible. To succeed in the innovation system development, development system stakeholders must hold and promote the improvement of five factors: linkages, partnership, network, positive interaction and synergy as a key success factor. In the innovation network shows the success of innovation depends on the effective interaction. The interaction showed linkages for strengthening regional innovation system needs to be cultivated in supporting innovation and business activity and then become an innovation network. Interactions and relationships can be made by advances in information and communicationstechnology, where it is also one important factor to establish science and technology. Advances in information and communications technology contribute to promoting and realizing the potential of the region in facing and overcoming obstacles and challenges of region. Based on the observations of the importance of an innovation network in the region will need to be an analysis of inter-actor network conditions that support the strengthening of the Regional Innovation System. For the pilot area is the town of Cimahi (West Java).