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  • Stereoselective metal-free ...
    Genoni, Andrea; Benaglia, Maurizio; Massolo, Elisabetta; Rossi, Sergio

    Chemical communications, 01/2013, Letnik: 49, Številka: 75
    Journal Article

    The enantioselective organocatalytic reduction of trifluoromethyl aryl and alkyl ketoimines afforded the corresponding fluorinated amines with high chemical and stereochemical efficiency. The Lewis base catalyzed reaction with trichlorosilane led to chiral products with a trifluoromethyl group directly linked to the newly generated stereocenter typically in >90% yield and up to 98% e.e.