ABSTRACT The Spitzer-Cosmic Assembly Deep Near-infrared Extragalactic Legacy Survey (S-CANDELS; PI G.Fazio) is a Cycle 8 Exploration Program designed to detect galaxies at very high redshifts ( ). To mitigate the effects of cosmic variance and also to take advantage of deep coextensive coverage in multiple bands by the Hubble Space Telescope (HST) Multi-cycle Treasury Program CANDELS, S-CANDELS was carried out within five widely separated extragalactic fields: the UKIDSS Ultra-deep Survey, the Extended Chandra Deep Field South, COSMOS, the HST Deep Field North, and the Extended Groth Strip. S-CANDELS builds upon the existing coverage of these fields from the Spitzer Extended Deep Survey (SEDS), a Cycle 6 Exploration Program, by increasing the integration time from SEDS' 12 hr to a total of 50 hr but within a smaller area, 0.16 deg2. The additional depth significantly increases the survey completeness at faint magnitudes. This paper describes the S-CANDELS survey design, processing, and publicly available data products. We present Infrared Array Camera (IRAC) dual-band catalogs reaching to a depth of 26.5 AB mag. Deep IRAC counts for the roughly 135,000 galaxies detected by S-CANDELS are consistent with models based on known galaxy populations. The increase in depth beyond earlier Spitzer/IRAC surveys does not reveal a significant additional contribution from discrete sources to the diffuse Cosmic Infrared Background (CIB). Thus it remains true that only roughly half of the estimated CIB flux from COBE/DIRBE is resolved.