The article addresses the priorities of US relations with European Union. The victory of Joseph Biden and Democratic Party on the elections of 2020 signified quite radical twist in US foreign policy. The election slogan «America is back» which won the White House for the Democratic Party and Congress, means restoration of transatlantic relationship, damaged by the previous administration. Growing cooperation between the U.S. and E.U. is defined by a long term trend towards global competitiveness between Western democracies led by the United States against Asian autocracies headed by China. Besides, another impetus towards transatlantic relations was given by Russia’s special military operation in Ukraine. The institutions of bilateral relations established by the Biden and Obama administration were used for coordinating the measures to support Ukraine, adopt new sanctions against Russia and general cooperation tracks between Western countries