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Lee, Nelson; Wong, Chun Kwok; Chan, Paul K.S; Lindegardh, Niklas; White, Nicholas J; Hayden, Frederick G; Wong, Edward H.C; Wong, Ka Shing; Cockram, Clive S; Sung, Joseph J.Y; Hui, David S.C
Emerging infectious diseases, 01/2010, Letnik: 16, Številka: 1Journal Article
We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios >3), and interleukin-6, CXCL10/IP-10, but no evidence of viral neuroinvasion. Patients recovered without sequelae. Hyperactivated cytokine response may play a role in pathogenesis.
