We present the discovery of a transiting hot Jupiter orbiting HIP 67522 (Teff ∼ 5650 K; M* ∼ 1.2M ) in the 10-20 Myr old Sco-Cen OB association. We identified the transits in the TESS data using our custom notch filter planet search pipeline and characterize the system with additional photometry from Spitzer; spectroscopy from SOAR/Goodman, SALT/HRS, LCOGT/NRES, and SMARTS/CHIRON; and speckle imaging from SOAR/HRCam. We model the photometry as a periodic Gaussian process with transits to account for stellar variability and find an orbital period of days and radius of R⊕. We also identify a single transit of an additional candidate planet with radius R⊕ that has an orbital period of 23 days. The validated planet HIP 67522b is currently the youngest transiting hot Jupiter discovered and is an ideal candidate for transmission spectroscopy and radial velocity follow-up studies, while also demonstrating that some young giant planets either form in situ at small orbital radii or else migrate promptly from formation sites farther out in the disk.