At present, the economic ties between countries worldwide are getting closer and closer. In a world where the internet industry is developing rapidly, Digital learning and ICT applications in blockchain have gradually matured. This paper takes digital learning and ICT blockchain application in e-commerce as the main research object, The rapid development of e-commerce has been promoted through the extensive application of digital learning and information and communication technology blockchain in e-commerce. Digital learning and information and communication technology solve the problems of e-commerce payment with encryption characteristics and security and openness in blockchain; At the same time, the information can be traced and cannot be tampered with to solve the quality problem of e-commerce goods. In a real sense to promote the sustainable development of the field of e-commerce, this study provides new ideas and guidance for the blockchain framework of e-learning and ICT in e-commerce.