ABSTRACT Recent high angular resolution ( ) ALMA observations of the 1.1 mm continuum and of HCO+ J = 3-2 and HCN J = 3-2 gas toward the binary protostar IRS 43 reveal multiple Keplerian disks that are significantly misaligned ( ), both in inclination and position angle and also with respect to the binary orbital plane. Each stellar component has an associated circumstellar disk while the binary is surrounded by a circumbinary disk. Together with archival VLA measurements of the stellar positions over 25 years, and assuming a circular orbit, we use our continuum measurements to determine the binary separation, , and its inclination, . The misalignment in this system suggests that turbulence has likely played a major role in the formation of IRS 43.