•Cona rift is the easternmost rift in the Himalayas.•Multi-thermochronometers suggest 3.0–2.3 Ma rift initiation.•Initiation of Himalayan rifts youngs monotonically eastward.•Lithospheric flow driven by asynchronous GPE gradients caused E–W extension. Several competing hypotheses have been proposed to explain east-west extension observed across the Himalayan orogen, based primarily on observations from the western and central Himalaya. They make predictions for the temporal and spatial patterns of deformation in the eastern Himalaya. These tectonic models include radial spreading or oroclinal bending of the Himalayan arc, oblique convergence of the Indian continent, tearing or lateral detachment of the Indian slab and eastward flow of lithosphere. Here, for the first time we constrain the activity history of the Cona rift, the only north-trending rift currently recognized in the eastern Himalaya, based on biotite and K-feldspar 40Ar/39Ar and zircon and apatite (U–Th)/He thermochronology, to evaluate these proposed rifting mechanisms. Low-temperature thermochronological results suggest that the Cona rift is the youngest rift system in the Himalayas: after a slow phase of exhumation since ∼14 Ma (∼0.2–0.13 mm/yr), normal faulting initiated here at ∼3.0–2.3 Ma with a fault slip rate of ∼3.8–1.6 mm/yr and a horizontal extension magnitude of ∼2–5 km. Analysis of rifting across the Himalayas shows that rift initiation ages young eastward, which is matched by eastward decreasing rift-extension magnitudes. Monotonically eastward younging rift development is consistent with the tectonic model involving eastward lithospheric flow driven by Indian slab dynamics and coupled asynchronous gravitational potential energy gradients.