Aerosol optical depth (AOD) is one of essential atmosphere parameters for climate change assessment as well as for total ecological situation study. This study presents long-term data (2000-2017) on time-space distribution and trends in AOD over various ecological regions of China, received from Moderate Resolution Imaging Spectroradiometer (MODIS) (combined Dark Target and Deep Blue) and Multi-angle Imaging Spectroradiometer (MISR), based on satellite Terra. Ground-based stations Aerosol Robotic Network (AERONET) were used to validate the data obtained. AOD data, obtained from two spectroradiometers, demonstrate the significant positive correlation relationships (r = 0.747), indicating that 55% of all data illustrate relationship among the parameters under study. Comparison of results, obtained with MODIS/MISR Terra and AERONET, demonstrate high relation (r = 0.869 - 0.905), while over 60% of the entire sampling fall within the range of the expected tolerance, established by MODIS and MISR over earth (±0.05 ± 0.15 × AOD and 0.05 ± 0.2 × AOD ) with root-mean-square error (RMSE) of 0.097-0.302 and 0.067-0.149, as well as low mean absolute error (MAE) of 0.068-0.18 and 0.067-0.149, respectively. The MODIS search results were overestimated for AERONET stations with an average overestimation ranging from 14 to 17%, while there was an underestimate of the search results using MISR from 8 to 22%.