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Wang, Guotai; Zuluaga, Maria A.; Pratt, Rosalind; Aertsen, Michael; Doel, Tom; Klusmann, Maria; David, Anna L.; Deprest, Jan; Vercauteren, Tom; Ourselin, Sébastien
Medical image analysis, December 2016, 2016-12-00, 20161201, Letnik: 34Journal Article
•Minimal user interaction is needed for a good segmentation of the placenta.•Random forests with high level features improved the segmentation.•Higher accuracy than state-of-the-art interactive segmentation methods.•Co-segmentation of multiple volumes outperforms single sparse volume based method. Segmentation of the placenta from fetal MRI is challenging due to sparse acquisition, inter-slice motion, and the widely varying position and shape of the placenta between pregnant women. We propose a minimally interactive framework that combines multiple volumes acquired in different views to obtain accurate segmentation of the placenta. In the first phase, a minimally interactive slice-by-slice propagation method called Slic-Seg is used to obtain an initial segmentation from a single motion-corrupted sparse volume image. It combines high-level features, online Random Forests and Conditional Random Fields, and only needs user interactions in a single slice. In the second phase, to take advantage of the complementary resolution in multiple volumes acquired in different views, we further propose a probability-based 4D Graph Cuts method to refine the initial segmentations using inter-slice and inter-image consistency. We used our minimally interactive framework to examine the placentas of 16 mid-gestation patients from MRI acquired in axial and sagittal views respectively. The results show the proposed method has 1) a good performance even in cases where sparse scribbles provided by the user lead to poor results with the competitive propagation approaches; 2) a good interactivity with low intra- and inter-operator variability; 3) higher accuracy than state-of-the-art interactive segmentation methods; and 4) an improved accuracy due to the co-segmentation based refinement, which outperforms single volume or intensity-based Graph Cuts.
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