E-viri
PDF
Recenzirano
Odprti dostop
-
Kolaj-Robin, Olga; Russell, David; Hayes, Kevin A.; Pembroke, J. Tony; Soulimane, Tewfik
FEBS letters, May 22, 2015, Letnik: 589, Številka: 12Journal Article
The Cation Diffusion Facilitators (CDFs) form a family of membrane-bound proteins capable of transporting zinc and other heavy metal ions. Involved in metal tolerance/resistance by efflux of ions, CDF proteins share a two-modular architecture consisting of a transmembrane domain (TMD) and C-terminal domain (CTD) that protrudes into the cytoplasm. Discovery of a Zn2+ and Cd2+ CDF transporter from a marine bacterium Maricaulis maris that does not possess the CTD questions current perceptions regarding this family of proteins. This article describes a new, CTD-lacking subfamily of CDFs and our current knowledge about this family of proteins in the view of these findings.
