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Amemiya, Haley M; Kundaje, Anshul; Boyle, Alan P
Scientific reports, 06/2019, Letnik: 9, Številka: 1Journal Article
Functional genomics assays based on high-throughput sequencing greatly expand our ability to understand the genome. Here, we define the ENCODE blacklist- a comprehensive set of regions in the human, mouse, worm, and fly genomes that have anomalous, unstructured, or high signal in next-generation sequencing experiments independent of cell line or experiment. The removal of the ENCODE blacklist is an essential quality measure when analyzing functional genomics data.
