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Pirok, Bob W. J; Stoll, Dwight R; Schoenmakers, Peter J
Analytical chemistry, 01/2019, Letnik: 91, Številka: 1Journal Article
Liquid chromatography (LC) is an incredibly successful analytical separation tool. Its versatility is unprecedented because of the many different separation modes and because almost all samples can be dissolved in some kind of solvent, ranging from water to organic solvents to strong acids or bases. Conditions can be found to separate almost all pairs of analytes. Here, Pirok et al explore some 160 applications of two-dimensional LC (2D-LC) techniques that have been published in 2016, 2017, or 2018. They also discuss progress in methodology in the same period, obstacles to successful implementation and application of LC X LC techniques and possible remedies.
