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Schunk, M.; Reitmeir, P.; Schipf, S.; Völzke, H.; Meisinger, C.; Thorand, B.; Kluttig, A.; Greiser, K.-H.; Berger, K.; Müller, G.; Ellert, U.; Neuhauser, H.; Tamayo, T.; Rathmann, W.; Holle, R.
Diabetic medicine, 20/May , Letnik: 29, Številka: 5Journal Article
Diabet. Med. 29, 646–653 (2012) Aims To estimate population values of health‐related quality of life (HRQL) in subjects with and without Type 2 diabetes mellitus across several large population‐based survey studies in Germany. Systematic differences in relation to age and sex were of particular interest. Methods Individual data from four population‐based studies from different regions throughout Germany and the nationwide German National Health Interview and Examination Survey (GNHIES98) were included in a pooled analysis of primary data (N = 9579). HRQL was assessed using the generic index instrument SF‐36 (36‐item Short Form Health Survey) or its shorter version, the SF‐12 (12 items). Regression analysis was carried out to examine the association between Type 2 diabetes and the two component scores derived from the SF‐36/SF‐12, the physical component summary score (PCS‐12) and the mental component summary score (MCS‐12), as well as interaction effects with age and sex. Results The PCS‐12 differed significantly by −4.1 points in subjects with Type 2 diabetes in comparison with subjects without Type 2 diabetes. Type 2 diabetes was associated with significantly lower MCS‐12 in women only. Higher age was associated with lower PCS‐12, but with an increase in MCS‐12, for subjects with and without Type 2 diabetes. Conclusions Pooled analysis of population‐based primary data offers HRQL values for subjects with Type 2 diabetes in Germany, stratified by age and sex. Type 2 diabetes has negative consequences for HRQL, particularly for women. This underlines the burden of disease and the importance of diabetes prevention. Factors that disadvantage women with Type 2 diabetes need to be researched more thoroughly.
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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in: SICRIS
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