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  • Interaction of Lymphocytes ...
    Svirshchevskaya, E. V.; Poltavtseva, R. A.; Beletskii, I. P.; Selezneva, I. I.; Savilova, A. M.; Sukhikh, G. T.

    Bulletin of experimental biology and medicine, 08/2016, Letnik: 161, Številka: 4
    Journal Article

    We studied the interaction of neural stem cells and dental pulp-derived mesenchymal stem cells with lymphocytes from autologous and heterologous donors. Flow cytometry analysis with the use of CFSE-labeled lymphocytes demonstrated an increase in the content of proliferating CD8, CD16 and CD56 cells, but not CD4 cells in cultures of HLA-DR-negative mesenchymal stromal cells from the dental pulp co-cultured with lymphocytes. In neural cultures expressing HLA-DR, all subpopulations of T cells and NK cells were activated. No differences between the autologous and heterologous cultures were revealed.