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Jiang, Peiyong; Tong, Yu K; Sun, Kun; Cheng, Suk H; Leung, Tak Y; Chan, K C Allen; Chiu, Rossa W K; Lo, Yuk Ming Dennis
Clinical chemistry (Baltimore, Md.), 02/2017, Letnik: 63, Številka: 2Journal Article
In a previous study, the sizes of cell-free DNA in maternal plasma were reported to be positively correlated with the DNA methylation level (4). ...we quantified the proportion of long DNA fragments (>150 bp) for each plasma sample. Future work could involve the validation of the present data using an expanded sample size, as well as the identification of methylation markers whose methylation levels would be more strongly correlated with the gestational age.
