E-viri
Recenzirano
Odprti dostop
-
Barrantes-Martínez, Yudy V.; Liévano, Martha; Ruiz, Álvaro J.; Cuéllar- Rios, Isabel; Paola Valencia, Diana; Wiesner-Reinhold, Melanie; Schreiner, Monika; Ballesteros-Vivas, Diego; Guzmán-Pérez, Valentina
Journal of functional foods, August 2022, 2022-08-00, 2022-08-01, Letnik: 95Journal Article
Display omitted •Tropaeolum majusL. is a plant rich in bioactive compounds such as glucosinolates and their secondary metabolites isothiocyanates.•Nasturtium intervention reduces lipid metabolism biomarkers in prediabetic subjects.•The edible plant nasturtium reduces oxidized LDL and cardiovascular risk indexes.•Benzyl isothiocyanate reduces cardiovascular risk indexes and oxidized LDL. Nasturtium (Tropaeolum majus L.) is a plant rich in bioactive compounds such as phenolic compounds, glucosinolates (GLS) and their hydrolyzed metabolites isothiocyanates (ITCs), which modulate signaling pathways related to lipid and carbohydrate metabolism. This randomized crossover trial explored the effect of intervention with a freeze-dried nasturtium drink on insulin response and lipid profile in prediabetic subjects. Ten (10) patients were randomly assigned to the following treatments: NT (nasturtium) and PLC (placebo) for 4 weeks and after this time the treatments were crossed for another 4 weeks. Biomarkers related to insulin resistance and lipid profile were measured at the beginning and the end of the intervention with each treatment. The consumption of 15 g NT (681 μmol of benzyl glucosinolate)/dose week for four (4) weeks resulted in a significant decrease in the concentration of LDL cholesterol (LDLc), Oxidized LDL (ox-LDL), Castelli's risk index I and II (TC/HDLc, and LDLc/HDLc) and Atherogenic Coefficient (non-HDLc)/HDLc). The results suggest that the nasturtium consumption might have a modulating effect on biomarkers related to cardiovascular disease, altered in subjects with chronic diseases, including type 2 diabetes. This study is the first in vivo study to explore the chronic effect of T. majus consumption in patients with prediabetes and shows the importance of continuing to explore this effect in studies with a larger number of participants.
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.