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Troina, A.A.; Figueiredo, M.S.; Moura, E.G.; Boaventura, G.T.; Soares, L.L.; Cardozo, L.F.M.F.; Oliveira, E.; Lisboa, P.C.; Passos, M.A.R.F.; Passos, M.C.F.
Food and chemical toxicology, 02/2010, Letnik: 48, Številka: 2Journal Article
We evaluated the effects of maternal dietary flaxseed during lactation on milk composition, body composition and sexual function of the adult female offspring. The dams were fed a control casein diet (C) or flaxseed diet (F, 25%) throughout lactation. F mothers showed higher serum 17β-estradiol (E 2) and leptin at weaning. F mother’s milk had lower total cholesterol (TC) and higher E 2 and leptin. The offspring of F dams showed lower body mass (BM), body fat mass (BFM), visceral fat mass (VFM), TC and triglycerides (TG) and higher serum leptin and E 2 at 21 days. F offspring showed delayed puberty onset. At 150 days, these offspring presented higher BFM, VFM, TC, TG, E 2 and lower relative uterine weight and lower progesterone. In conclusion, flaxseed during lactation did affect the lipid profile, adipose tissue and sexual function in adulthood, probably due hyperestrogenism and hyperleptinemia at weaning.
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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