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Brewster, Richard C; Gavins, Georgina C; Günthardt, Barbara; Farr, Sarah; Webb, Kimberly M; Voigt, Philipp; Hulme, Alison N
Chemical communications (Cambridge, England), 01/2016, Letnik: 52, Številka: 82Journal Article
Rapid, site-selective modification of cysteine residues with chloromethyl-triazole derivatives generates pseudo-acyl sLys motifs, mimicking important post-translational modifications. Near-native biotinylation of peptide and protein substrates is shown to be site-selective and modified histone H4 retains functional activity.
