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Sauer, Andrew J., BS; Moss, Arthur J., MD; McNitt, Scott, MS; Peterson, Derick R., PhD; Zareba, Wojciech, MD, PhD; Robinson, Jennifer L., MS; Qi, Ming, PhD; Goldenberg, Ilan, MD; Hobbs, Jenny B., BA; Ackerman, Michael J., MD, PhD; Benhorin, Jesaia, MD; Hall, W. Jackson, PhD; Kaufman, Elizabeth S., MD; Locati, Emanuela H., MD, PhD; Napolitano, Carlo, MD; Priori, Silvia G., MD, PhD; Schwartz, Peter J., MD; Towbin, Jeffrey A., MD; Vincent, G. Michael, MD; Zhang, Li, MD
Journal of the American College of Cardiology, 01/2007, Letnik: 49, Številka: 3Journal Article
Long QT Syndrome in Adults Andrew J. Sauer, Arthur J. Moss, Scott McNitt, Derick R. Peterson, Wojciech Zareba, Jennifer L. Robinson, Ming Qi, Ilan Goldenberg, Jenny B. Hobbs, Michael J. Ackerman, Jesaia Benhorin, W. Jackson Hall, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, MD, Silvia G. Priori, Peter J. Schwartz, Jeffrey A. Towbin, G. Michael Vincent, Li Zhang The clinical course and risk factors for cardiac events in genotype-confirmed adult patients with long QT syndrome (LQTS) were investigated. The severity of LQTS in adulthood can be risk stratified with information regarding genotype, gender, corrected QT duration, and history of cardiac events. Beta-blockers effectively reduce but do not eliminate the risk of both syncopal and life-threatening cardiac events in adult patients with mutation-confirmed LQTS.
