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Recenzirano
Odprti dostop
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Catelli, Chiara; Faccioli, Eleonora; Silvestrin, Stefano; Lorenzoni, Giulia; Luzzi, Luca; Bennett, David; Schiavon, Marco; Campisi, Alessio; Bargagli, Elena; Dell'Amore, Andrea; Rea, Federico
Cancers, 01/2024, Letnik: 16, Številka: 3Journal Article
The accurate selection of the recipient is a crucial aspect in the field of lung transplantation (LTX), especially if patients were previously affected by oncological disease. The aim of this bicentric retrospective study was to evaluate short- and long-term outcomes in patients with previous oncological disease or unknown neoplasia found on native lungs submitted to LTX, compared to a control group. A total of 433 patients were included in the analysis, 31 with malignancies (Group 1) and 402 without neoplastic disease (Group 2). The two groups were compared in terms of short- and long-term outcomes. Patients in Group 1 were older (median age 58 years vs. 50 years, = 0.039) and mostly affected by idiopathic pulmonary fibrosis (55% vs. 40% = 0.002). Even though in Group 1 a lower rate of late post-operative complications was found (23% vs. 45%, = 0.018), the median overall survival (OS) was lower compared to the control group (10 months vs. 29 months, = 0.015). LTX represents a viable therapeutic option for patients with end-stage lung disease and a history of neoplastic disease. However, every case should be carefully debated in a multidisciplinary setting, considering oncological (histology, stage, and proper disease free-interval) and clinical factors (patient's age and comorbidities). A scrupulous post-transplant follow-up is especially mandatory in those cases.
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Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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