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Zhai, Lijie; Dey, Mahua; Lauing, Kristen L; Gritsina, Galina; Kaur, Rajwant; Lukas, Rimas V; Nicholas, M. Kelly; Rademaker, Alfred W; Dostal, Carlos R; M Cusker, Robert H; Raizer, Jeffrey J; Parsa, Andrew T; Bloch, Orin; Wainwright, Derek A
Journal of clinical neuroscience, 12/2015, Letnik: 22, Številka: 12Journal Article
Highlights • We discuss the complex link between indoleamine 2,3 dioxygenase 1 (IDO1), tryptophan (Trp) and kynurenine (Kyn) in glioblastoma (GBM) patients. • We identify a potential new prognostic tool for GBM patient stratification. • We found that differences in the Kyn/Trp ratio appear ⩾10 weeks post-surgery. • We introduce novel physiologically-relevant clinical data from GBM patients.
