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  • The role of TRPC6 in seizur...
    Kim, Y.-J; Kang, T.-C

    Neuroscience, 10/2015, Letnik: 307
    Journal Article

    Highlights • TRPC6 plays an important role in neuronal activity and neuronal survivals. • TRPC6 expression was down-regulated in the dentate gyrus in epileptic rats. • TRPC6 knockdown increased seizure susceptibility in the rat dentate gyrus. • TRPC6 knockdown promoted programed necrosis in dentate granule cells following SE. • TRPC6 may inhibit seizure susceptibility and SE-induced neuronal damage.