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    Bienvenu, Anne-Lise; Bleyzac, Nathalie; Richard, Jean-Christophe; Leboucher, Gilles

    Critical care (London, England), 09/2020, Letnik: 24, Številka: 1
    Journal Article

    ...the use of corticosteroids or anti-IL6 antibody in addition to standard of care is proposed for critically ill patients with COVID-19. ...corticosteroids are well-known risk factors for IFI and identified as a negative outcome predictor of invasive aspergillosis 4, whereas IFI were reported in patients treated with anti-IL6 antibody 5. ...it is expected that incidence of IFI may increase with the more extensive use of corticosteroids or other immunomodulating therapies, and this, mostly in patients with risk factors for CAPA such as older age, initial antibiotic usage of beta-lactamase inhibitor combination, and chronic obstructive pulmonary disease (COPD) 1. Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.