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Borriello, Lucia; Seeger, Robert C; Asgharzadeh, Shahab; DeClerck, Yves A
Cancer letters, 09/2016, Letnik: 380, Številka: 1Journal Article
Highlights • There is now evidence that the extracellualr matrix and normal cells in the tumor microenvironment of neuroblstoma tumors and metastases contribute to progression. • The communication between neuroblstoma cells and stromal cells is through a combination of adhesion-dependent and adhesion-independent mechnnisms. • New therapies targeting these mechanims are now tested in multiple early phase clinical trials.
