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Fischer, D. J.; Epstein, J. B.; Yao, Y; Wilkie, D. J.
Supportive care in cancer, 03/2014, Letnik: 22, Številka: 3Journal Article
Purpose Oral conditions are established complications in terminally ill cancer patients. Yet despite significant morbidity, the characteristics and impact of oral conditions in these patients are poorly documented. The study objective was to characterize oral conditions in terminally ill cancer patients to determine the presence, severity, and the functional and social impact of these oral conditions. Methods This was an observational clinical study including terminally ill cancer patients (2.5–3-week life expectancy). Data were obtained via the Oral Problems Scale (OPS) that measures the presence of subjective xerostomia, orofacial pain, taste change, and the functional/social impact of oral conditions and a demographic questionnaire. A standardized oral examination was used to assess objective salivary hypofunction, fungal infection, mucosal erythema, and ulceration. Regression analysis and t test investigated the associations between measures. Results Of 104 participants, most were ≥50 years of age, female, and high-school educated; 45 % were African American, 43 % Caucasian, and 37 % married. Oral conditions frequencies were: salivary hypofunction (98 %), mucosal erythema (50 %), ulceration (20 %), fungal infection (36 %), and other oral problems (46 %). Xerostomia, taste change, and orofacial pain all had significant functional impact; p < .001, p = .042 and p < .001, respectively. Orofacial pain also had a significant social impact ( p < .001). Patients with oral ulcerations had significantly more orofacial pain with a social impact than patients without ulcers ( p = .003). Erythema was significantly associated with fungal infection and with mucosal ulceration ( p < .001). Conclusions Oral conditions significantly affect functional and social activities in terminally ill cancer patients. Identification and management of oral conditions in these patients should therefore be an important clinical consideration.
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Vir: Osebne bibliografije
in: SICRIS
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